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NIZO, FrieslandCampina and Nutrileads are joining forces in substantiating Health Benefits

Published: 07-07-2017

Human Challenge Models to Accelerate Health Benefits Development

NIZO, Royal FrieslandCampina and NutriLeads are joining forces in the CHALLENGE consortium. CHALLENGE aims to develop new food ingredients that will support resistance to infections, as well as affordable and predictive research models in healthy volunteers to allow companies accelerated market access.

Alwine Kardinaal, project leader at NIZO: “The combined research power of the companies involved is unique and will enable us to take the next step in predicting health benefits with the use of Human Challenge Studies. Especially in nutrition research, challenge studies are a unique approach to induce a physiological response in healthy subjects, and to investigate how an active ingredient modulates this response. Given NIZO’s reputation with i.e. the ETEC model, we are confident to lead this exciting project”.

Ruud Albers, CEO of NutriLeads: “NutriLeads strongly believes in the Human Challenge Model
concept. The CHALLENGE consortium is a logical next step in substantiating the immune supportive
effect of our lead ingredient, a novel Immune Modulating Plant Polysaccharide”.
Marjolijn Bragt, research leader at FrieslandCampina explains: “FrieslandCampina wants to
contribute towards feeding the world population and focuses on improving its products to contribute
to the consumer needs. The innovative power of CHALLENGE is expressed in the evaluation of
translational biomarkers for infants and children. ”

The CHALLENGE project has a total budget of 3.7 million Euro, of which 1.5 million Euro will be cofinanced
by the European Union and EFRO OP-Oost. The subsidy was granted in Q2 2017; first results
will become available later this year.

About NIZO
NIZO is world leading in contract research for better food and health. We operate one of the most
advanced R&D centers in the world and bring the latest food technologies to life in our food grade
processing center. We focus on the development and applications of innovations for the global food
and health industry. Our customers value their gains in product quality, sustainability, cost
effectiveness and speed to market. We are continuously looking for new ways of improving food
products, and at the same time quality of life. NIZO is a private and independent company, with
headquarters in Ede, the Netherlands.

About NutriLeads
NUTRILEADS is a startup that develops nutritional ingredients with demonstrated health effects.
NutriLeads aims to catalyze nutritional health innovation in the food industry by partnering with
relevant companies to identify promising lead ingredients, developing sustainable and commercially
viable production processes, managing the regulatory challenges and initiating scientific & clinical
programs to substantiate the health effects of these ingredients. Together we will bring the benefits
of the proprietary ingredients to patients and consumers.

About Royal FrieslandCampina 
Every day FrieslandCampina provides millions of consumers all over the world with dairy products
that are rich in valuable nutrients. With annual revenue of 11 billion euros, FrieslandCampina is one
of the world’s six largest dairy companies.

FrieslandCampina supplies consumer products such as dairy-based beverages, infant nutrition, cheese
and desserts in many European countries, in Asia and in Africa. In addition, products are supplied to
professional customers, including cream and butter products to bakeries and catering companies. In
addition, FrieslandCampina produces ingredients and half-finished products for manufacturers of
infant nutrition, the food industry and the pharmaceutical sector around the world.

FrieslandCampina has branch offices in 33 countries and employs a total of just under 22,000 people.
FrieslandCampina’s products find their way to more than 100 countries. The Company’s central office
is based in Amersfoort, the Netherlands. FrieslandCampina’s activities are divided into five marketoriented
business groups: Consumer Products Europe, Middle East & Africa; Consumer Products Asia;
Consumer Products China; Cheese, Butter & Milkpowder and Ingredients. The Company is fully owned
by Zuivelcoöperatie FrieslandCampina U.A, and with 18,900 member dairy farmers in the
Netherlands, Germany and Belgium it is one of the world’s largest dairy cooperatives.